The International Hydrogen Standards Association (IHSA) is an international organization focused on determining the standards for measuring hydrogen gas, and establishing guidelines for its therapeutic use; was established in September 2016.
The definitions and standards set forth by IHSA will help to advance scientific research in the academic and medical communities, provide guidance to governmental agencies and educational institutions, encourage responsibility in the areas of design, sales and marketing for the therapeutic hydrogen industry, and provide protection for the consumer by offering certifications for hydrogen technologies in accordance with established IHSA safety and performance and standards.
Gas chromatography (GC) will be considered the primary method for measuring molecular hydrogen. GC should be the most reliable method for specialists in chemical analyses. In brief, this method requires the transfer of H2 from the aqueous phase to the gas phase using a tightly closed vessel, where hydrogen concentration can be measured by GC. The standard operating procedures (SOP) for measurement by GC will soon be determined by IHSA to mitigate systematic errors.
Source: IHSA Official Website
IHSA will also adopt a secondary method using an electrode that is specific to hydrogen. Several electrodes are currently available commercially; however, each has merits and shortcomings. Thus, one electrode will be carefully selected for the measurement, and the standard operating procedures (SOP) will be established by IHSA. While there may be other suitable options for general consumer use, these will not be considered for use in IHSA performance certifications. For example, IHSA may recommend different brands of electrodes, sensors, use of approved redox titration reagents, etc. However, methods that depend on the measurement of the oxidation-reduction potential (ORP) to estimate hydrogen in water, which incorporate electrodes which are not specific to hydrogen, are discouraged. Although a negative ORP is one of the characteristics of hydrogen water, ORP itself does not show the hydrogen concentration. Thus, technologies which rely upon measurement of ORP should not be used as a method to measure the hydrogen concentration.